Research constitutes an integral part of our work in the department. We believe that neurosurgery is such an exclusive field that it cannot be understood only as a medical discipline. Research is an essential part of our daily routine. The main points of interest in research correspond with general issues of neurosurgery. Systematic research is funded from grant projects but our department has other small projects which do not require funding from state aid.
In vascular neurosurgery, we focus our research on the issue of carotid artery stenosis and the correlation of various diagnostic methods with anatomical findings. In recent years, we have been also interested in the comparison between surgical and endovascular treatment of this disease. In the field of brain ischemia, we study the significance of cerebrovascular reserve capacity, indication of extra-intracranial anastomoses and electrophysiological correlates of the disease. We also pay a lot of attention to electrophysiological peroperative monitoring of patients who have undergone surgery for brain ischemia. We have assessed several studies dealing with the comparison of surgical and endovascular treatment of patients with aneurysms. Our main field of interest in this area is the neuropsychological effects of subarachnoid hemorrhage treated with different methods. We regularly assess the data of our groups of patients with arteriovenous malformations and cavernomas.
In neurooncology, we are primarily interested in the genetics of brain tumors, which we find essential in the future development of neurosurgery. From the surgical point of view, our attention is aimed at the correlation and potential of peroperative magnetic resonance imaging and fluorescence techniques. Our research includes the study of imaging techniques, functional magnetic resonance imaging and pre-, per- and post-operative tractographies. Pituitary adenomas are the subject of study primarily in relation to peroperative magnetic resonance imaging and the potential of endoscopic endonasal technique. We also research the potential of this technique in other diseases of the skull base. In meningiomas, our main field of interest is the character of growth and the brain-tumor relation. Smaller projects deal primarily with intradural spinal tumors, specifically with intraspinal tumors and their peroperative monitoring by means of both electrophysiology and magnetic resonance imaging.
A traditional focus of research is hydrocephalus, especially normotensive hydrocephalus. We attempt to further specify indications for shunts and the third ventriculostomy with the help of sophisticated tests. We also perform research in congenital anomalies and epileptosurgery in children in cooperation with the pediatric neurosurgical department in Krč Hospital.
We closely cooperate with the Prague Epileptosurgery Association in the field of functional neurosurgery with our primary focus being pathological findings of epileptogenous zones and peroperative corticography. In the research of pain, we concentrate especially on the pathophysiology of neurovascular conflict and its electrophysiological and radiological correlation. Our study of modulation techniques falls within a university research programme.
Spinal research is primarily focused on surgeries. The research of various stabilization techniques, miniinvasive methods and complex procedures is regularly evaluated. Our research also includes the study of degenerative diseases of cervical spine, craniocervical junction and frontal access to thoracic and lumbar spine. A specifically followed group includes patients with rheumatoid artritis.
This website includes a list of publications and grant projects which document our scope of research in detail.
